One of the problems with extreme outer solar-system missions is the necessity (when launched with EELVs) to make multiple passes of other planets to build up velocity. In one of the papers referred to in the thread, it was mentioned that a conventionally-launched Uranus probe would be loaded down with heavy thermal protection for a Venus fly-by.
Could this be a useful application of SLS? How much could SLS with the as-planned DUUS throw through a direct TJI or TSI to slingshot towards Uranus?
My opening caveat: I am skeptical of all science missions that propose using SLS. The cost is prohibitive.
That said, one of the potential advantages of SLS for planetary missions is that it can eliminate gravity assist trajectories. This can have many benefits. Off the top of my head:
-eliminates need for unnecessary mass, like thermal protection for Venus flybys
-reduces time to reach destination
-eliminates flybys of Earth with RTGs (a safety concern)
-could reduce overall mission lifetime required testing (for instance, the spacecraft only has to be certified to operate for 8 years instead of 14 I think that the last one could be interesting for somebody to explore.)
There are C3 (throw-weight/energy) charts for outer planets missions using SLS. I think I posted some of them in another thread. They are for direct missions to the destinations and show how much mass you can throw directly to Europa, Saturn, and Uranus. For Uranus even with SLS (and I think even with SLS Block II) the line still falls off the graph, meaning that you still cannot do a direct mission to Uranus. However, I'm not sure that's a concern, since I presume that most outer planets missions are going to swing past Jupiter. However, however, Jupiter isn't always in the right position, so that eliminates your opportunities. The point of a direct mission is that you can launch pretty much whenever you want to, or at least during a lot more windows.
Somebody at JPL probably has a nice little computer program that does all of this stuff, telling them the available launch windows for a whole bunch of mission options and allowing them to alter payload, time, etc.